Presentations

Rapid Raman Microspectroscopyand Imaging: The Role of the Electron-Multiplied CCD (EMCCD)

Presentation made at FACSS 2006, Orlando. The talk presents research conducted jointly with Dr. Michael Morris and his group at the University of Michigan

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Watching Single Motor Molecules at Work: From Cellular Function to Bionanotechnology

Stefan Diez - Bionanotechnology and Optical Technology Development

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Breaking the Diffraction Limit Captures Single Molecule Dynamics

Ragan Robertson - Biological Sciences at Columbia University, NY, USA

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A Single Photon Emission Microscope System for I-125 Imaging in Small Animals

L. J. Meng, Department of Nuclear Engineering and Radiological Sciences, University of Michigan
Neal Clinthorne, Department of Radiology,University of Michigan at Ann Arbor
Scott Skinner, Milton Gross, VA Medical Center, Ann Arbor, Michigan
Rick .H. Hay, Van Vandel Research Institute, Grand Rapid, Michigan

I-125 decays via electron capture. The three highest photon emission probabilities for I-125 decay are 76% at 27.5 keV, 13% at 31 keV, and 7% at 35 keV. I-125 has a half-life of 60.14 days. The combination the low energy and long half-life offers some advantages for SPECT imaging.

Small animal imaging using I-125 labeled radiotracers is gaining increasing popularity. Over the past several years, researchers from the V. A. Medical Center in Ann Arbor the Van Andel Research Institute in Grand Rapid, Michigan have long been using I-125 labeled antibodies, peptides and other compounds as screening agents in development of diagnostic and therapeutic radiopharmaceuticals for various type of cancers.

Due to the low photon energy, it is possible to collimate and detect the photons with a very high accuracy. It is possible to achieve an imaging spatial resolution that is down to <100 microns level. There has been substantial efforts in trying to do microscopic imaging in small animals Download Paper

High Precision Photometry of Quasars using the Andor FI iXon

Dr. Niall Smith, Dr. Aidan O’Connor, Mr. Alan Giltinan, Mr. Stephen O’Driscoll, Cork Institute of Technology
Prof. Stefan Wagner, Mr. Marcus Hauser, LSW, Heidelberg

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Experiments with quantum gases, quantum gates, and atom fibers

Prof. Michael Chapman School of Physics, Georgia Institute of Tecnology

Ultracold atomic physics for quantum control and measurementDownload Presentation

Cooperative Electrophysiology and Multiwavelength Imaging with Live Cells

Michael Delay - INDEC BioSystems

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Laser spectroscopy and Raman scattering: from excited states to biomedicine

John McGarvey, School of Chemistry, Queens University, Belfast, N.Ireland

  • Laser spectroscopy at QUB and Raman application overview
  • Raman - strengths and challenges
  • Preliminary analysis of EMCCD

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What’s up with EM-CCDs II?

EM-CCDs and Fluorescence microscopy.

Jim Pawley, Zoology Department, University of Wisconsin-Madison, WI, USA

To answer the question of the hour What do microscopists really want? Sensitivity!! ...but what kind? Download Presentation

EMCCDs & Digital CDS techniques

Jean Luc Gach, Observatoire de Marseille

  • Needs for low noise CCDs
  • EMCCDs theory
  • EMCCDs results
  • EMCCDs controller considerations
  • Digital CDS theory
  • Digital CDS results

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The Atmospheric Physics Laboratory of University College London studies the upper atmospheres of the earth and the other planets in the solar system. Observational techniques are augmented by computer modelling

Ian McWhirter, Atmospheric Physics Laboratory of University College London

We can measure the characteristics of this light and determine directly winds and temperatures in the neutral atmosphere

  • Optical methods are the only way to measure neutral winds and temperatures directly
  • There are many anomalies between measured neutral winds and those derived from computer models and radar measurements of charged particles
  • Optically measured neutral winds vary from derived winds by up to 100% and temperatures by 100s of degrees
  • Calculations of neutral ion coupling assumptions. Derived winds do not take into account small scale structure and the inertia of the thermosphere

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Directly observing intra-cellular dynamics with 4D microscopy and single molecule microscopy - the challenges ahead.

Derek Toomre, Yale University, US

  • Overview of present and emerging biological applications that will require fast ultrasensitive imaging.
  • Overview of the parameters and challenges of advanced cellular imaging
  • Educational yet entertaining: Take YOU on an visual ride, from just barely skimming the cell surface, to deep into cells.

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Optimising EMCCDs

How to extract the ultimate performance

Donal Denvir, Andor Technology, Belfast, N.Ireland

  • Spurious Charge – Clock Induced Charge
  • Darksignal and Cooling
  • Vacuum technology
  • Baseline Shift
  • Horizontal Smearing
  • Ageing Effects
  • Dynamic Range

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Digital EMCCD Camera Technology -Overview

Colin Coates, Andor Tecnology, Belfast, N.Ireland

  • What is a sensitive camera and why are they important?
  • Competing Technologies.
  • Impact Ionization and EMCCD Gain.
  • Applications in Ultra Low-light Microscopy.
  • Future?

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